Diopower15
Wild Yam Extract with 15% Diosgenin
Diopower15 is a wild yam (Dioscorea opposita) extract with no less than 15% diosgenin. Dipower comes from a wild yam called Sanyaku, which has been used in traditional Chinese herbal medicine known as Kanpo before 0AD. Sanyaku can be found written as an ingredient for perennial youth and long life in Shennong Becaojing, the oldest Chinese book on agriculture and medicinal plants.
Studies show diosgenin-rich yam can improve cognitive functions in healthy adults.* Studies have also shown that diosgenin-rich yam can promote healthy levels of sex hormones, lipids and antioxidants in postmenopausal women, while also reducing markers of risk for breast cancer and cardiovascular disease.*
Diopower15 is manufactured with the highest grade Sanyaku called Kai-Sanyaku. The Pro-Diosgenin content in the Kai-Sanyaku that is used is 4-8 times higher than normal Sanyaku. Diopower15 is extracted from Kai-Sanyaku using a Japanese patented method discovered by Prof. Gen-Ichiro Nonaka. Most wild yam extracts contain Pro-Diosgenin (saponin), not Diosgenin (sapogenin). However, because Pro-Diosgenin is not very bioavailable, in Diopower15, the Pro-Diosgenin is converted to Diosgenin by hydrolysis making it bioavailable for humans. Diopower15 is standardized for at least 15% Diosgenin content.
Features:
PLANT-BASED
NATURAL
SAFE
BIOAVAILABLE
NO CARRIERS
PRODUCED IN GMP FACILITIES
KOSHER
VEGAN
RESEARCH-BASED
Specification
Appearance:
Color:
Odor:
Mesh Size:
Diosgenin:
Source:
Powder
White/Light Yellow
Slight Yam Smell
80 Mesh
NLT 15%
Wild Yam (Dioscorea opposita)
Research
Diopower may improve cognitive function in individuals with moderate cognitive impairment (Inada et al 2024).
Diopower may enhance cognitive function, shown in a placebo-controlled, randomized, double-blind crossover study of healthy adults (Tohda et al. 2017).
Diosgenin-rich yam helped improve the status of sex hormones, lipids, and antioxidants in healthy postmenopausal women, while also decreasing levels of carcinogenic estrogen metabolites and markers of oxidative stress suggesting reduction in the risk of breast cancer and cardiovascular diseases (Tohda et al. 2017).
In a study with a human skin equivalent model, diosgenin enhanced DNA synthesis and restored keratinocyte proliferation in aged skin (Tada et al. 2009).
Diosgenin is safe and did not accelerate tumor growth in breast cancer-burdened mice (Tada et al. 2009).
Diosgenin was found to facilitate repair of damaged neurons and improve memory dysfunction in a transgenic mouse model of Alzheimer’s disease (Tohda et al. 2012, Tohda et al. 2017).
Mechanism of action of diosgenin was found to be through activating the 1,25D3-MARRS pathway, that may be a critical pathway in anti-Alzheimer’s Disease therapy (Tohda et al. 2012, Tohda et al. 2018).
Diosgenin was found to enhance neuronal excitation and memory function in normal mice (Tohda et al. 2013).
*The statements made have not been evaluated by the U.S. Food and Drug administration or any other regulatory authority. Guzen’s products are not intended for use to diagnose, treat, cure, or prevent any disease.
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