SCP-II®

Salmon Collagen Proteoglycan Complex

 
 
 

SCP-II® is the next generation of joint and skin health supplementation. SCP-II® is a complex of both undenatured type II collagen and undenatured proteoglycan, the two components that make up our joint cartilage. SCP-II® is a research-based ingredient that has shown in human studies to be effective in relieving joint pain and improving mobility. It has shown in a human study to be even more effective at relieving knee pain than glucosamine, and at a much smaller dose. Proteoglycan has also shown in a human study to improve skin condition.

SCP-II® is naturally extracted from salmon nasal cartilage in Hokkaido, Japan and contains 40% undenatured proteoglycan and 40% undenatured type II collagen. We especially love our SCP-II because it is sustainably and ethically sourced: it comes from the nasal cartilage of wild-caught salmon that would otherwise be wasted!

Features:

NON-GMO

MADE IN JAPAN

SAFE

SMALL DOSE

NO CARRIERS

RESEARCH-BASED

NATURAL

SUSTAINABLE

FISH DERIVED

Specification

Country of Origin:
Appearance:
Color:
Odor:
Taste:
Undenatured Type II Collagen:
Undenatured Proteoglycan:

Japan
Powder
White/Light Yellow
Odorless
Neutral/Slightly Salty
40%
40%

Research

Human studies suggest that Undenatured Type II Collagen and Undenatured Proteoglycan may help to*: 

  • Improve knee pain in individuals with Osteoarthritis

  • Improve knee pain in healthy individuals

  • Improve joint flexibility and mobility in healthy individuals

  • Have a protective effect on cartilage metabolism of individual with severe or constant knee pain

  • Improve and prevent knee inflammation 

  • Improve human skin condition, including skin elasticity, wrinkles, facial pores, blotches, moisture and smoothness 

 

Joint Pain

There are currently six human studies regarding undenatured Type II Collagen and undenatured Proteoglycan and their efficacy in decreasing knee pain and improving mobility.

The figure below is from a randomized, double-blind, placebo-controlled study conducted in 2016. It shows a statistically significant improvement in knee pain in the test group that was given SCP-II compared to the placebo group. The test group that took SCP-II also showed a statistically greater improvement than the control group that took glucosamine.

Kuriyama Y, Narumi M, et al. Translated: Effects of Taking Salmon Nasal Cartilage Extract on Knee Joint Pain. J. New Rem. & Clin. Vol. 65 No. 11, 2016.

Kuriyama Y, Narumi M, et al. Translated: Effects of Taking Salmon Nasal Cartilage Extract on Knee Joint Pain. J. New Rem. & Clin. Vol. 65 No. 11, 2016.

 

Skin Health

The figures below are from a randomized, double-blind, controlled study conducted in 2015. The results show that those who took salmon proteoglycan had a significant reduction in the number of wrinkles underneath the eyes compared to the placebo group (4A) and the number of conspicuous pores and darkened pores were also significantly reduced from baseline (4B). In the group that ingested salmon proteoglycan, the number of blotches in the skin showed significant change in contrast to the placebo group (4C).

Takahashi T, el al. Ingestion of Salmon Nasal Cartilage-Derived Proteoglycan Improves Skin Condition: A Randomized, Double-Blind, Controlled Study. Immun, Endoc. & Metab. Agents in Med. Chem., 2015, Vol.15, No.2;160-166

Takahashi T, el al. Ingestion of Salmon Nasal Cartilage-Derived Proteoglycan Improves Skin Condition: A Randomized, Double-Blind, Controlled Study. Immun, Endoc. & Metab. Agents in Med. Chem., 2015, Vol.15, No.2;160-166

In the same study, analysis of skin looseness confirmed that salmon proteoglycan improved the elasticity of skin. The smaller the gap between the red circle (drawn when face is turned to the front) and the blue circle (drawn when lying on their face) showed a greater improvement in skin looseness.

Takahashi T, el al. Ingestion of Salmon Nasal Cartilage-Derived Proteoglycan Improves Skin Condition: A Randomized, Double-Blind, Controlled Study. Immun, Endoc. & Metab. Agents in Med. Chem., 2015, Vol.15, No.2;160-166

Takahashi T, el al. Ingestion of Salmon Nasal Cartilage-Derived Proteoglycan Improves Skin Condition: A Randomized, Double-Blind, Controlled Study.
Immun, Endoc. & Metab. Agents in Med. Chem., 2015, Vol.15, No.2;160-166

 

*The statements made have not been evaluated by the U.S. Food and Drug administration or any other regulatory authority. Guzen’s products are not intended for use to diagnose, treat, cure, or prevent any disease.

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